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A blast in rural Tennessee that leveled an explosives plant and was felt for miles around killed 16 people and left no survivors, authorities said.

The actor, known for her quirky, vibrant manner and depth was 79. Across her decades-long career, she worked with prominent filmmakers including Francis Ford Coppola, Woody Allen and Nancy Meyers.

Sources tell NPR that more than 100 employees have been laid off at the Substance Abuse and Mental Health Agency. The Centers for Disease Control and Prevention had some cuts reversed late Saturday.

Alt.Latino host Anamaria Sayre tells the story of how Chilean puppet show 31 Minutos became an international sensation after their Tiny Desk performance.

The far-right leader of Venezuela's opposition party said that the current president is illegitimate and called for his removal.

President Trump's announcement comes days before active duty members would have missed their first full paycheck as the shutdown of the federal government continues.

The shutdown is forcing the closure of a number of America's beloved cultural institutions starting Sunday. Twenty-one Smithsonian museums, its research centers and the National Zoo are all affected.

The small town of Leland, Miss., was rocked by the shooting, which took place late Friday.

At 92, Cameroon's President aul Biya is running for an eighth term on Sunday — a reminder of how Africa's aging leaders continue to cling to power, even as their nations face unrest, corruption, and calls for change.

October 11 is the "International Day of the Girl" on the United Nations calendar. These photos pay tribute to the spirit of girls in a world where they face many obstacles.

Mangione's lawyers asked a federal judge to dismiss some criminal charges, including the only count for which he could face the death penalty, from a federal indictment brought against him.

National Coming Out Day is Oct. 11. To celebrate and honor LGBTQ+ people who have come out and those who want to, NPR readers share how they told their loved ones.