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Biden and Trump will hold their first presidential debate tonight. Scientists think understanding how the brain removes waste and toxins may help treat a broad range of disorders.

NPR's Scott Simon speaks with conductor Marin Alsop and violinist Nema Robinson about the importance of mentoring young musicians.

The state currently bans most abortions after 15 weeks of pregnancy. That will drop to six weeks, with a few exceptions — a timetable that abortion rights advocates say is hard to meet

The British government has pushed the plan as a way to deter asylum-seekers from taking boats to Britain. But the U.N. human rights office has warned aviation authorities not to take part.

Control of Congress could run through Arizona, with competitive House and Senate races that will be set after today’s primaries. Trump has endorsed some of the GOP candidates, including two rivals.

A birthday and a spate of bad polls highlight the one weakness Biden cannot really address. He was 78 when he took office. He'd be 86 leaving a second term.

It's been a banner year for women's college basketball. Now, with March Madness upon us, we've talked with some of the star players ready to go big in the NCAA tournament.

After former President Donald Trump and Arizona GOP Senate candidate Kari Lake distanced themselves from the law, some abortion rights opponents are left wondering who they can count on.

The espionage trial for Gershkovich, a Wall Street Journal correspondent, has begun in Russia's Ural mountain capital of Yekaterinburg — the same city where he was detained 15 months ago.

Australian police say a knife attack in Sydney that wounded a bishop and a priest during a church service as worshippers watched online and in person, and sparked a riot was an act of terrorism.

Synagogues around the U.S. are having a lively discussion about how Israel is waging the war in Gaza, trying to balance care for the Jewish community with empathy for those suffering in Gaza.

Mike Casey tells NPR that the scale of spying against the United States is "impressive and terrifying." He says: "More players are getting into it with more tools, going after more targets."