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The U.S. has registered over half a million clinical trials since 2000. Here's a look at the business and ethics of human medical experimentation through the eyes of a volunteer.

The album "Little Old You" tackles big themes, including the mysteries of the natural world, as well as silly ones like gargling.

Three men indicted for the March shooting death of Long Branch teen Tristan Reeves. Suspects arrested in October now face murder charges in a 10-count indictment.

Holmdel CEO Anthony Tepedino faces federal charges in a $5M fraud scheme tied to shell companies and fake invoices. The case follows mass layoffs at Allstate Sales Group.

NPR is tracking the record number of congressional lawmakers — now more than one in eight current members — who have announced plans to retire or run for a different office in 2026.

Far-Flung Postcards is a weekly series in which NPR's international team shares moments from their lives and work around the world.

Rep. Mike Lawler says House Speaker Mike Johnson is correct in saying the health care system isn't working, but allowing ACA subsidies to expire without a plan to address rising costs is "idiotic."

President Trump's lawsuit alleges that the BBC's fall 2024 documentary was "a brazen attempt" to harm his re-election. The BBC has apologized but rejects his claim.

Whether you plan to head out to the theater or binge from the couch, our critics have gathered together their favorite films and TV shows of 2025.

A decade ago, the self-proclaimed Islamic State group held vast swaths of territory across Iraq and Syria, but President Trump declared it destroyed in 2019.

A new NPR/PBS News/Marist poll finds 70% of Americans say things have become too unaffordable and have a dim outlook on the economy and President Trump's handling of it.

Discover a broad range of this year's most compelling classical recordings, including symphonic booty-shakers, mystic violin, pipe organ prog and a guided tour of 18th century German chart-toppers.